Dictyostelium discoideum
نویسندگان
چکیده
Dictyostelium discoideum is a cellular slime mold [4] that serves as an important model organism [5] in a variety of fields. Cellular slime molds have an unusual life cycle. They exist as separate amoebae, but after consuming all the bacteria in their area they proceed to stream together to form a multicellular organism. These features make them a valuable tool for studying developmental processes and also for investigating the evolution [6] of multicellularity. Long thought to be a type of fungus, it has recently been shown that slime molds in fact bear no relation to fungi. Rather, they form the Mycetozoa, which consists of three distinct groups: plasmodial slime molds; cellular slime molds; and the Protostelia. The cellular slime molds are characterized by a life cycle that includes periods of both multicellularity and unicellularity.
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Cellular and Molecular Analysis of NDR and LATS Kinases in Dictyostelium
Ich versichere hiermit ehrenwörtlich, dass die vorgelegte Dissertation von mir selbständig und ohne unerlaubte Hilfe angefertigt ist. NdrA of Dictyostelium localizes to the centrosome and is required for efficient phagocytosis. Traffic, in press. cytokinesis in Dictyostelium discoideum. Dictyostelium discoideum by a SIN-related pathway. Eur. discoideum is regulated by a SIN-related pathway. of ...
متن کاملDiaphanous-related formins: characterization of mouse mDia1, and ForA/dDia3 from Dictyostelium discoideum amoebae
(2007) ForA is a Diaphanous-related formin required for directed cell motility in Dictyostelium discoideum. The American Society for Cell Biology, Dijon, France, Dynamic interplay between cytoskeletal and membrane systems, Abstract: 17. (2008) The actinome of Dictyostelium discoideum in comparison to actins and actin-related protein from other organisms. Characterization of the Ste20-like kinas...
متن کاملEvolutionary crossroads in developmental biology: Dictyostelium discoideum.
Dictyostelium discoideum belongs to a group of multicellular life forms that can also exist for long periods as single cells. This ability to shift between uni- and multicellularity makes the group ideal for studying the genetic changes that occurred at the crossroads between uni- and multicellular life. In this Primer, I discuss the mechanisms that control multicellular development in Dictyost...
متن کاملA G protein-based model of adaptation in Dictyostelium discoideum.
A new model is proposed based on signal transduction via G proteins for adaptation of the signal relay process in the cellular slime mold Dictyostelium discoideum. The kinetic constants involved in the model are estimated from Dictyostelium discoideum and other systems. A qualitative analysis of the model shows how adaptation arises, and numerical computations show that the model agrees with ob...
متن کاملCharacterisation of Vasodilator-Stimulated Phosphoprotein DdVASP, a third profilin isoform and Ste-20 like kinases from Dictyostelium discoideum
Diese Dissertation wurde selbständig und ohne unerlaubte Hilfsmittel angefertigt. (2005). The Diaphanous-related formin dDia2 is required for the formation and maintenance of filopodia. (2006). Characterisation of the Ste20-like kinase Krs1 of Dictyostelium discoideum. Eur. (2003) STE20-like kinases and their role in the actin cytoskeleton in Dictyostelium discoideum. The Ste20-like kinase DST1...
متن کاملIsolation of germination mutants of Dictyostelium discoideum.
A simple method to separate spores from amoebae of Dictyostelium discoideum has been devized and used to isolate spore germination mutants. A subclass of these mutants is temperature sensitive for germination and growth.
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